1358734-35-6
1358734-35-6
Chemical Structure
RU-0415529
- CAS No.: 1358734-35-6
- Formula:C21H29N3O4S
- Molecular Weight:419.54
InChIKey: XBICIDNIOXYNGU-UHFFFAOYSA-N
SMILES: CC1CCN(S(=O)(C2=C(C)N(C)C(C(NCC3=CC=CC=C3OC)=O)=C2)=O)CC1
Biological Activity: RU-0415529 is an orally active inhibitor for SARS-CoV-2 nonstructural protein 14 (NSP14) with an IC50 of 356 nM. RU-0415529 binds to the SAH-stabilized cap binding pocket, inhibits viral RNA methylation and the viral replication. RU-0415529 exhibits anti-infectious activity in mouse models[1].
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RU-0415529 | RU-0415529 is an orally active inhibitor for SARS-CoV-2 nonstructural protein 14 (NSP14) with an IC50 of 356 nM. RU-0415529 binds to the SAH-stabilized cap binding pocket, inhibits viral RNA methylation and the viral replication. RU-0415529 exhibits anti-infectious activity in mouse models. | |||||||||||||||||||||
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References
Keywords
