1370001-71-0
1370001-71-0
Chemical Structure
BMS-351
- CAS No.: 1370001-71-0
- Formula:C15H12F3N3
- Molecular Weight:291.27
IUPAC Name: 4-(4-methylpyridin-3-yl)-1-(2,2,2-trifluoroethyl)-1H-benzo[d]imidazole
InChIKey: OFFVLUDFSIUVMI-UHFFFAOYSA-N
SMILES: FC(F)(CN1C=NC2=C1C=CC=C2C3=C(C)C=CN=C3)F
Biological Activity: BMS-351 (compound 18) is a potent, oral active, nonsteroidal CYP17A1 lyase inhibitor with the IC50 values of 19 nM and 4 nM aganist human CYP17A1 and cynomolgus monkeys CYP17A1,respectively. BMS-351 can be used for the study of castration-resistant prostate cancer[1].
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BMS-351 | BMS-351 (compound 18) is a potent, oral active, nonsteroidal CYP17A1 lyase inhibitor with the IC50 values of 19 nM and 4 nM aganist human CYP17A1 and cynomolgus monkeys CYP17A1,respectively. BMS-351 can be used for the study of castration-resistant prostate cancer. | |||||||||||||||||||||
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