137319-34-7
137319-34-7
Chemical Structure
Dehydroeffusol
- CAS No.: 137319-34-7
- Formula:C17H14O2
- Molecular Weight:250.29
IUPAC Name: 1-methyl-5-vinylphenanthrene-2,7-diol
InChIKey: GSSPKCPIRDPBQE-UHFFFAOYSA-N
SMILES: OC1=CC=C2C3=C(C=C)C=C(O)C=C3C=CC2=C1C
Biological Activity: Dehydroeffusol is a phenanthrene from medicinal herb Juncus effuses. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. It shows very low toxicity[1][2].
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Dehydroeffusol | 99.55% | Dehydroeffusol is a phenanthrene from medicinal herb Juncus effuses. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. It shows very low toxicity. | ||||||||||||||||||||
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References
- [1]. Zhang B, et al. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. Biochem Pharmacol. 2016 Mar 15;104:8-18. [Content Brief]
- [2]. Liu W, et al. Dehydroeffusol effectively inhibits human gastric cancer cell-mediated vasculogenic mimicry with low toxicity. Toxicol Appl Pharmacol. 2015 Sep 1;287(2):98-110. [Content Brief]
Keywords
