1380228-30-7
1380228-30-7
Chemical Structure
INU-152
- CAS No.: 1380228-30-7
- Formula:C20H13F2N7O3S
- Molecular Weight:469.42
IUPAC Name: N-(3-((3-(9H-purin-6-yl)pyridin-2-yl)amino)-2,4-difluorophenyl)furan-3-sulfonamide
InChIKey: ACIXGVIVJZJKNT-UHFFFAOYSA-N
SMILES: FC(C=CC(NS(=O)(C1=COC=C1)=O)=C2F)=C2NC3=NC=CC=C3C4=NC=NC5=C4N=CN5
Biological Activity: INU-152 is a potent and selective B-Raf inhibitor. INU-152 reduces tumor cell proliferation, enhances autophagy, and induces apoptosis by inhibiting B-Raf activity. INU-152 exhibits significant cytotoxicity against cancer cells transformed with v-Ha-ras (Ras-NIH 3T3). INU-152 can be utilized in cancer research[1].
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INU-152 | INU-152 is a potent and selective B-Raf inhibitor. INU-152 reduces tumor cell proliferation, enhances autophagy, and induces apoptosis by inhibiting B-Raf activity. INU-152 exhibits significant cytotoxicity against cancer cells transformed with v-Ha-ras (Ras-NIH 3T3). INU-152 can be utilized in cancer research. | |||||||||||||||||||||
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