138154-39-9
138154-39-9
Chemical Structure
C-1311
- CAS No.: 138154-39-9
- Formula:C20H22N4O2
- Molecular Weight:350.41
IUPAC Name: 5-((2-(diethylamino)ethyl)amino)-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one
InChIKey: CUNDRHORZHFPLY-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=CC(O)=C2)N(C=N3)C4=C3C=CC(NCCN(CC)CC)=C14
Biological Activity: C-1311 shows to inhibit the catalytic activity of DNA topoisomerase II in vitro and in tumour cells. C-1311 prolongs G2 arrest followed by G2 to M transit and cell death during mitosis in the process of mitotic catastrophe[1].
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C-1311 | C-1311 shows to inhibit the catalytic activity of DNA topoisomerase II in vitro and in tumour cells. C-1311 prolongs G2 arrest followed by G2 to M transit and cell death during mitosis in the process of mitotic catastrophe. | |||||||||||||||||||||
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References
Keywords
