1384097-28-2
Chemical Structure
(R)-GSK-F1
- CAS No.: 1384097-28-2
- Formula:C27H18F5N5O4S
- Molecular Weight:603.52
InChIKey: MSRFVAYVUUHQCN-UHFFFAOYSA-N
SMILES: O=C1C2=C(N=C(N1C3=C(C(F)(F)F)C=CC=C3)N)C=CC(C4=CC(S(=O)(NC5=CC=C(C=C5F)F)=O)=C(OC)N=C4)=C2
Biological Activity: (R)-GSK-F1 is the R-type isomer of GSK-F1 (HY-100603). GSK-F1 (Compound F1) is an orally active PI4KA inhibitor with pIC50 values of 8.0, 5.9, 5.8, 5.9, 5.9 and 6.4 against PI4KA, PI4KB, PI3KA, PI3KB, PI3KG and PI3KD, respectively. GSK-F1 can be used for HCV infection research[1].
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(R)-GSK-F1 | (R)-GSK-F1 is the R-type isomer of GSK-F1 (HY-100603). GSK-F1 (Compound F1) is an orally active PI4KA inhibitor with pIC50 values of 8.0, 5.9, 5.8, 5.9, 5.9 and 6.4 against PI4KA, PI4KB, PI3KA, PI3KB, PI3KG and PI3KD, respectively. GSK-F1 can be used for HCV infection research. | |||||||||||||||||||||
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Keywords