PI4KB
PI4KIIIβ is the Golgi-resident type III phosphatidylinositol 4-kinase, encoded by PI4KB. Recruited to the trans-Golgi network through interactions with small GTPases of the ARF family and with lipid effectors, it builds the PI4P gradient that drives budding of secretory vesicles and recruitment of adaptor and lipid-transfer proteins. PI4KIIIβ also sustains PI4P at the plasma membrane under certain stimuli and is a well-documented host dependency of enteroviruses, including poliovirus and rhinovirus, which redistribute the kinase to replication organelles, making it a target for broad-spectrum antiviral strategies. Unlike PI4KIIIα, PI4KIIIβ is highly sensitive to the inhibitor PIK93, a property widely used to dissect Golgi PI4P function.
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PI4KB Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
