13878-10-9
13878-10-9
Chemical Structure
Caprochlorone
- CAS No.: 13878-10-9
- Formula:C19H19ClO3
- Molecular Weight:330.81
IUPAC Name: 4-(2-chlorobenzyl)-5-oxo-4-phenylhexanoic acid
InChIKey: JACSSWDJQLXNOO-UHFFFAOYSA-N
SMILES: ClC(C=CC=C1)=C1CC(C(C)=O)(C2=CC=CC=C2)CCC(O)=O
Biological Activity: Caprochlorone has antiviral activity against orthopoxvirus. Caprochlorone can inhibit cell penetration by virus, also delays release of newly formed virus from the cell. Caprochlorone decreases the titers of influenza virus in infected-mice lungs[1][2][3].
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Caprochlorone | Caprochlorone has antiviral activity against orthopoxvirus. Caprochlorone can inhibit cell penetration by virus, also delays release of newly formed virus from the cell. Caprochlorone decreases the titers of influenza virus in infected-mice lungs. | |||||||||||||||||||||
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References
- [1]. Smee DF, Sidwell RW. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003;57(1-2):41-52. [Content Brief]
- [2]. Stanfield FJ, Haff RF, Stewart RC. The antiviral activity of caprochlorone. Proc Soc Exp Biol Med. 1967;125(1):297-303. [Content Brief]
- [3]. LIU OC, et al. Studies on the chemotherapy of viral infections. II. The effect of caprochlorone on influenza virus infections in mice. J Immunol. 1957;78(3):222-227. [Content Brief]
Keywords
