1396337-04-4
1396337-04-4
Chemical Structure
Auglurant
Synonym(s): VU0424238
- CAS No.: 1396337-04-4
- Formula:C16H12FN5O2
- Molecular Weight:325.30
IUPAC Name: N-(5-fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide
InChIKey: RBAHIIPVJVMACF-UHFFFAOYSA-N
SMILES: CC1=NC(C(NC2=CC=C(F)C=N2)=O)=CC(OC3=CN=CN=C3)=C1
Biological Activity: Auglurant (VU0424238) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human). Auglurant (VU0424238) has an acceptable CNS penetration[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Auglurant | 99.34% | Auglurant (VU0424238) is a novel and selective mGlu5 antagonist with an IC50 value of 11 nM (rat) and an IC50 value of 14 nM (human). Auglurant (VU0424238) has an acceptable CNS penetration. | ||||||||||||||||||||
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References
Keywords
