1398112-32-7
Chemical Structure
Metalaxyl-M-d6
- CAS No.: 1398112-32-7
- Formula:C15H15D6NO4
- Molecular Weight:285.37
IUPAC Name: 2-phenyl-2-(piperidin-2-yl-2,3,3,4,4,5,5,6,6-d9)acetic acid hydrochloride
InChIKey: ZQEIXNIJLIKNTD-GMGXQYKBSA-N
SMILES: COC([C@@H](C)N(C1=C(C=CC=C1C([2H])([2H])[2H])C([2H])([2H])[2H])C(COC)=O)=O
Biological Activity: Metalaxyl-M-d6 ((R)-Metalaxyl-d6) is the deuterium labeled Metalaxyl-M (HY-B0843A). Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase, which exerts fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. Metalaxyl-M can also be used to induce inflammation in hepatocytes and regulate tryptophan metabolism. Metalaxyl-M can be used in ecotoxicology studies[1][2][3].
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Metalaxyl-M-d6 | Metalaxyl-M-d6 ((R)-Metalaxyl-d6) is the deuterium labeled Metalaxyl-M (HY-B0843A). Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase, which exerts fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. Metalaxyl-M can also be used to induce inflammation in hepatocytes and regulate tryptophan metabolism. Metalaxyl-M can be used in ecotoxicology studies. | |||||||||||||||||||||
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Metalaxyl-M (Standard) | 97.40% | Metalaxyl-M ((R)-Metalaxyl) (Standard) is the analytical standard of Metalaxyl-M (HY-B0843A). This product is intended for research and analytical applications. Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase, which exerts fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. Metalaxyl-M can also be used to induce inflammation in hepatocytes and regulate tryptophan metabolism. Metalaxyl-M can be used in ecotoxicology studies. | ||||||||||||||||||||
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Metalaxyl-M | 98.09% | Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase, which exerts fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. Metalaxyl-M can also be used to induce inflammation in hepatocytes and regulate tryptophan metabolism. Metalaxyl-M can be used in ecotoxicology studies. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Yinjun Zhang, et al. Bio-preparation of (R)-DMPM using whole cells of Pseudochrobactrum asaccharolyticum WZZ003 and its application on kilogram-scale synthesis of fungicide (R)-metalaxyl. Biotechnol Prog [Content Brief]
- [3]. OuYang MN, et al. The different toxic effects of metalaxyl and metalaxyl-M on Tubifex tubifex. Ecotoxicol Environ Saf. 2021 Jan 15;208:111587. [Content Brief]
