Benalaxyl-d5
Benalaxyl-d5 is the deuterium labeled Benalaxyl (HY-121109). Benalaxyl is a fungicide, but A. fumigatus isolates are intrinsically resistant to Benalaxyl.
For research use only. We do not sell to patients.
- CAS No.: 2714421-66-4
- Formula: C20H18D5NO3
- Molecular Weight:330.43
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 2714421-66-4
-
Unlabeled Cas 71626-11-4
-
Molecular Weight 330.43
-
Formula C20H18D5NO3
-
SMILES
CC(C(OC)=O)N(C1=C(C)C=CC=C1C)C(CC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Meneau I, et al. Azole and fungicide resistance in clinical and environmental Aspergillus fumigatus isolates. Med Mycol. 2005 May;43 Suppl 1:S307-11. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)