1401031-52-4
Chemical Structure
LSN2463359
- CAS No.: 1401031-52-4
- Formula:C16H15N3O
- Molecular Weight:265.31
IUPAC Name: N-isopropyl-5-(pyridin-4-ylethynyl)picolinamide
InChIKey: STAFRSGTRKNXHF-UHFFFAOYSA-N
SMILES: O=C(C1=NC=C(C=C1)C#CC2=CC=NC=C2)NC(C)C
Biological Activity: LSN2463359 is positive allosteric modulator of metabotropic glutamate 5 (mGlu5). LSN2463359 attenuates aspects of the behavioral response to administration of the competitive NMDA receptor antagonist. LSN2463359 selectively attenuates reversal learning deficits observed in the neurodevelopmental MAM E17 model[1]. LSN2463359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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LSN2463359 | 98.49% | LSN2463359 is positive allosteric modulator of metabotropic glutamate 5 (mGlu5). LSN2463359 attenuates aspects of the behavioral response to administration of the competitive NMDA receptor antagonist. LSN2463359 selectively attenuates reversal learning deficits observed in the neurodevelopmental MAM E17 model. LSN2463359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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LSN2463359 (Standard) | ≥98% | LSN2463359 (Standard) is the analytical standard of LSN2463359 (HY-110152). This product is intended for research and analytical applications. LSN2463359 is positive allosteric modulator of metabotropic glutamate 5 (mGlu5). LSN2463359 attenuates aspects of the behavioral response to administration of the competitive NMDA receptor antagonist. LSN2463359 selectively attenuates reversal learning deficits observed in the neurodevelopmental MAM E17 model. LSN2463359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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