1402818-99-8
1402818-99-8
Chemical Structure
hURAT1 inhibitor 2
- CAS No.: 1402818-99-8
- Formula:C17H11Br2FO3
- Molecular Weight:442.07
InChIKey: GIVTUZFBWDBWTM-UHFFFAOYSA-N
SMILES: O=C(C1=CC(Br)=C(O)C(Br)=C1)C2=C(CC)OC3=CC(F)=CC=C23
Biological Activity: hURAT1 inhibitor 2 (Compound 5) is an inhibitor of hURAT1 (uric acid transporter 1, SLC22A12) with an IC50 of 18 nM. hURAT1 inhibitor 2 also has a certain inhibitory effect on OATP1B1, with an IC50 value of 0.73 μM. hURAT1 inhibitor 2 can be used in the research of diseases related to abnormal uric acid metabolism, such as hyperuricemia and gout[1].
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hURAT1 inhibitor 2 | hURAT1 inhibitor 2 (Compound 5) is an inhibitor of hURAT1 (uric acid transporter 1, SLC22A12) with an IC50 of 18 nM. hURAT1 inhibitor 2 also has a certain inhibitory effect on OATP1B1, with an IC50 value of 0.73 μM. hURAT1 inhibitor 2 can be used in the research of diseases related to abnormal uric acid metabolism, such as hyperuricemia and gout. | |||||||||||||||||||||
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References
Keywords
