141-84-4
141-84-4
Chemical Structure
Rhodanine
- CAS No.: 141-84-4
- Formula:C3H3NOS2
- Molecular Weight:133.20
IUPAC Name: 2-thioxothiazolidin-4-one
InChIKey: KIWUVOGUEXMXSV-UHFFFAOYSA-N
SMILES: O=C1NC(SC1)=S
Biological Activity: Rhodanine is a selective Echovirus 12 proliferation inhibitor and intermediate. Rhodanine is used to determine tannase activity. Rhodanine can be used in the synthesis of anticancer and antibacterial agents[1][2][3][4][5].
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Rhodanine | 98.0% | Rhodanine is a selective Echovirus 12 proliferation inhibitor and intermediate. Rhodanine is used to determine tannase activity. Rhodanine can be used in the synthesis of anticancer and antibacterial agents. | ||||||||||||||||||||
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References
- [1]. Sing WT, et al. Arylalkylidene rhodanine with bulky and hydrophobic functional group as selective HCV NS3 protease inhibitor. Bioorg Med Chem Lett. 2001 Jan 22;11(2):91-4. [Content Brief]
- [2]. Enemuor S C, et al. Culture conditions for the production of a tannase of Aspergillus tamarii IMI388810 (B). African Journal of Biotechnology, 2009, 8(11).
- [3]. Eggers HJ, et al. Rhodanine: a selective inhibitor of the multiplication of echovirus 12. Science. 1970 Jan 16;167(3916):294-7. [Content Brief]
- [4]. AbdelKhalek A, et al. In Vitro Antibacterial Activity of Rhodanine Derivatives against Pathogenic Clinical Isolates. PLoS One. 2016 Oct 6;11(10):e0164227. [Content Brief]
- [5]. Gao J, et al. Fluorescent ferroptosis inducers leveraging the pharmacological activity of rhodanine to promote antitumor immunity. Science China Chemistry, 2025: 1-14.
Keywords
