1414808-96-0
Chemical Structure
Tryptamine guanosine carbamate
Synonym(s): TpGc
- CAS No.: 1414808-96-0
- Formula:C21H23N7O6
- Molecular Weight:469.45
IUPAC Name: ((2R,3S,4R,5R)-5-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl (2-(1H-indol-3-yl)ethyl)carbamate
InChIKey: WKHCFGWBMMFLHU-NVQRDWNXSA-N
SMILES: O[C@H]1[C@@H](O)[C@H](N2C3=C(C(N=C(N3)N)=O)N=C2)O[C@@H]1COC(NCCC4=CNC5=CC=CC=C45)=O
Biological Activity: Tryptamine guanosine carbamate (TpGc) is a selective HINT1 (histidine triad nucleotide-binding protein 1) inhibitor (Ki=34 μM, Kd=3.65 μM). Tryptamine guanosine carbamate significantly enhances morphine antinociception while preventing the development of tolerance[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Tryptamine guanosine carbamate | 99.79% | Tryptamine guanosine carbamate (TpGc) is a selective HINT1 (histidine triad nucleotide-binding protein 1) inhibitor (Ki=34 μM, Kd=3.65 μM). Tryptamine guanosine carbamate significantly enhances morphine antinociception while preventing the development of tolerance. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
