1416990-08-3
1416990-08-3
Chemical Structure
Lenalidomide-OH
- CAS No.: 1416990-08-3
- Formula:C13H12N2O4
- Molecular Weight:260.25
IUPAC Name: 3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione
InChIKey: JJUMFQGCQAUIFH-UHFFFAOYSA-N
SMILES: O=C(C(N(CC1=C2C=CC(O)=C1)C2=O)CC3)NC3=O
Biological Activity: Lenalidomide-OH is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-OH can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC BTK degrader SJF620 (HY-133137)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Lenalidomide-OH | 99.48% | Lenalidomide-OH is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-OH can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC BTK degrader SJF620 (HY-133137). | ||||||||||||||||||||
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References
Keywords
