14173-40-1
14173-40-1
Chemical Structure
PCPA methyl ester hydrochloride
Synonym(s): 4-Chloro-DL-phenylalanine methyl ester hydrochloride
- CAS No.: 14173-40-1
- Formula:C10H13Cl2NO2
- Molecular Weight:250.13
IUPAC Name: methyl 2-amino-3-(4-chlorophenyl)propanoate hydrochloride
InChIKey: GCBCWTWQAFLKJG-UHFFFAOYSA-N
SMILES: NC(CC1=CC=C(Cl)C=C1)C(OC)=O.Cl
Biological Activity: PCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride), a reversible tryptophan hydroxylase inhibitor, is a serotonin (5-HT) synthesis inhibitor. PCPA methyl ester hydrochloride crosses the blood brain barrier and reduces 5-HT central availability[1][2].
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PCPA methyl ester hydrochloride | 99.89% | PCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride), a reversible tryptophan hydroxylase inhibitor, is a serotonin (5-HT) synthesis inhibitor. PCPA methyl ester hydrochloride crosses the blood brain barrier and reduces 5-HT central availability. | ||||||||||||||||||||
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PCPA methyl ester hydrochloride (Standard) | ≥98% | PCPA methyl ester (hydrochloride) (Standard) is the analytical standard of PCPA methyl ester (hydrochloride) (HY-101456). This product is intended for research and analytical applications. PCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride), a reversible tryptophan hydroxylase inhibitor, is a serotonin (5-HT) synthesis inhibitor. PCPA methyl ester hydrochloride crosses the blood brain barrier and reduces 5-HT central availability. | ||||||||||||||||||||
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References
- [1]. Dool-Ri Oh, et al. Sedative and hypnotic effects of Vaccinium bracteatum Thunb. through the regulation of serotonegic and GABA A-ergic systems: Involvement of 5-HT 1A receptor agonistic activity. Biomed Pharmacother. 2019 Jan;109:2218-2227. [Content Brief]
- [2]. Fabio Bellia, et al. Transient serotonin depletion at adolescence, but not at early infancy, reduced subsequent anxiety-like behavior and alcohol intake in female mice. Psychopharmacology (Berl). 2021 Jan;238(1):215-225. [Content Brief]
