1426953-24-3
Chemical Structure
Thailanstatin C
- CAS No.: 1426953-24-3
- Formula:C30H46ClNO9
- Molecular Weight:600.14
IUPAC Name: 2-((2S,4S,5R,6R)-4-(chloromethyl)-4,5-dihydroxy-6-((1E,3E)-5-((2S,3S,5R,6R)-5-((S,Z)-4-(isobutyryloxy)pent-2-enamido)-3,6-dimethyltetrahydro-2H-pyran-2-yl)-3-methylpenta-1,3-dien-1-yl)tetrahydro-2H-pyran-2-yl)acetic acid
InChIKey: IUEAQIHFZAHMMU-WEDQMBCXSA-N
SMILES: C[C@@H](C[C@H]([C@H](O1)C)NC(/C=C\[C@H](C)OC(C(C)C)=O)=O)[C@@H]1C/C=C(C)/C=C/[C@@H]2[C@H]([C@@](O)(C[C@H](O2)CC(O)=O)CCl)O
Biological Activity: Thailanstatin C is a pre-mRNA splicing inhibitor (IC50= 6.84 μM) and antiproliferative agent from Burkholderia thailandensis MSMB43[1].
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Thailanstatin C | Thailanstatin C is a pre-mRNA splicing inhibitor (IC50= 6.84 μM) and antiproliferative agent from Burkholderia thailandensis MSMB43. | |||||||||||||||||||||
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Keywords
