1430420-02-2
Chemical Structure
HJC0123
- CAS No.: 1430420-02-2
- Formula:C24H16N2O3S
- Molecular Weight:412.46
IUPAC Name: N-(1,1-dioxidobenzo[b]thiophen-6-yl)-2-phenylquinoline-4-carboxamide
InChIKey: ZUYCAEIBKWUMND-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C2=C1)C=CS2(=O)=O)C3=CC(C4=CC=CC=C4)=NC5=CC=CC=C35
Biological Activity: HJC0123 is a STAT3 inhibitor. HJC0123 inhibits the proliferation of hepatic stellate cells and induces cell cycle arrest and apoptosis. HJC0123 reduces the phosphorylation, nuclear translocation and transcriptional activities of STAT3, increases the production of IL-6, inhibits the phosphorylation of Smad2/3 and down-regulates SOCS3. HJC0123 can be used in the study of liver fibrosis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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HJC0123 | 99.06% | HJC0123 is a STAT3 inhibitor. HJC0123 inhibits the proliferation of hepatic stellate cells and induces cell cycle arrest and apoptosis. HJC0123 reduces the phosphorylation, nuclear translocation and transcriptional activities of STAT3, increases the production of IL-6, inhibits the phosphorylation of Smad2/3 and down-regulates SOCS3. HJC0123 can be used in the study of liver fibrosis. | ||||||||||||||||||||
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Keywords
