1431329-47-3
Chemical Structure
Hemopressin(rat) TFA
- CAS No.: 1431329-47-3
- Formula:C55H78F3N13O14
- Molecular Weight:1202.28
InChIKey: FXBODCREWDDYNR-DFZCIRLNSA-N
SMILES: OC(C(F)(F)F)=O.OC([C@H](CC1=CN=CN1)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CCCCN)NC([C@@H](NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@@H]2CCCN2)=O)=O)=O)CC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O
Biological Activity: Hemopressin(rat) TFA is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin(rat) TFA is orally active, selective and inverse agonist of CB1 cannabinoid receptors. Hemopressin(rat) TFA exerts antinociceptive action in inflammatory pain models[1][2].
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Hemopressin(rat) TFA | Hemopressin(rat) TFA is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin(rat) TFA is orally active, selective and inverse agonist of CB1 cannabinoid receptors. Hemopressin(rat) TFA exerts antinociceptive action in inflammatory pain models. | |||||||||||||||||||||
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- [1]. Camila Squarzoni Dale, et al. Hemopressin: a novel bioactive peptide derived from the alpha1-chain of hemoglobin. em Inst Oswaldo Cruz. 2005 Mar;100 Suppl 1:105-6. [Content Brief]
- [2]. Elaine F Toniolo, et al. Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats. Peptides. 2014 Jun;56:125-31. [Content Brief]
Keywords
