143360-00-3
143360-00-3
Chemical Structure
SMIP004
- CAS No.: 143360-00-3
- Formula:C13H19NO
- Molecular Weight:205.30
IUPAC Name: N-(4-butyl-2-methylphenyl)acetamide
InChIKey: ZFVMECVBUGMWIX-UHFFFAOYSA-N
SMILES: CC1=C(NC(C)=O)C=CC(CCCC)=C1
Biological Activity: SMIP004 is a SKP2 E3 ligase inhibitor, which downregulates SKP2 and to stabilise p27. SMIP004 is a cancer cell selective apoptosis inducer of human prostate cancer cells[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SMIP004 | 99.79% | SMIP004 is a SKP2 E3 ligase inhibitor, which downregulates SKP2 and to stabilise p27. SMIP004 is a cancer cell selective apoptosis inducer of human prostate cancer cells. | ||||||||||||||||||||
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References
- [1]. Li C, et al. SKP2 promotes breast cancer tumorigenesis and radiation tolerance through PDCD4 ubiquitination. J Exp Clin Cancer Res. 2019 Feb 13;38(1):76. [Content Brief]
- [2]. Rico-Bautista E, Zhu W, Kitada S, Small Molecule-Induced Mitochondrial Disruption Directs Prostate Cancer Inhibition via UPR Signaling. Oncotarget. 2013 Jul 14. [Content Brief]
