143899-90-5
143899-90-5
Chemical Structure
Antidepressant agent 9
- CAS No.: 143899-90-5
- Formula:C17H24N2
- Molecular Weight:256.39
InChIKey: CYPHSPITDGFDMD-PVAVHDDUSA-N
SMILES: CN1[C@]2([H])[C@]3([H])[C@@](CC1)(CCCC3)C4=CC(N)=CC=C4C2
Biological Activity: Antidepressant agent 9 (Compound 24) is an orally active and BBB-penetrable NMDAR and SERT inhibitor with IC50 values of 3.50 μM and 1044 nM, respectively. Antidepressant agent 9 has good metabolic stability and plasma exposure. Antidepressant agent 9 can exert antidepressant-like activity in the mouse forced swim test[1].
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Antidepressant agent 9 | Antidepressant agent 9 (Compound 24) is an orally active and BBB-penetrable NMDAR and SERT inhibitor with IC50 values of 3.50 μM and 1044 nM, respectively. Antidepressant agent 9 has good metabolic stability and plasma exposure. Antidepressant agent 9 can exert antidepressant-like activity in the mouse forced swim test. | |||||||||||||||||||||
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References
Keywords
