144425-84-3
144425-84-3
Chemical Structure
L-703606
- CAS No.: 144425-84-3
- Formula:C27H29IN2
- Molecular Weight:508.44
IUPAC Name: (2S,3S)-2-benzhydryl-N-(2-iodobenzyl)quinuclidin-3-amine
InChIKey: WSLTYZVXORBNLB-SVBPBHIXSA-N
SMILES: IC(C=CC=C1)=C1CN[C@@H](C2CCN3CC2)[C@@H]3C(C4=CC=CC=C4)C5=CC=CC=C5
Biological Activity: L-703606 is a potent, selective antagonist of NK1 receptor. L-703606 can be used for study of gastric acid secretion[1][2].
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L-703606 | L-703606 is a potent, selective antagonist of NK1 receptor. L-703606 can be used for study of gastric acid secretion. | |||||||||||||||||||||
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References
- [1]. Minowa S, et al. Role of neuropeptide receptor systems in vanilloid VR1 receptor-mediated gastric acid secretion in rat brain. Eur J Pharmacol. 2004;486(3):317-324. [Content Brief]
- [2]. Francis BE, et al. Radioiodinated L-703,606: a potent, selective antagonist to the human NK1 receptor. Appl Radiat Isot. 1994;45(1):97-103. [Content Brief]
Keywords
