144980-29-0
Chemical Structure
Repinotan
Synonym(s): BAY x 3702 free base
- CAS. Nr.: 144980-29-0
- Formula:C21H24N2O4S
- Molecular Weight:400.49
IUPAC Name: (R)-2-(4-((chroman-2-ylmethyl)amino)butyl)benzo[d]isothiazol-3(2H)-one 1,1-dioxide
InChIKey: YGYBFMRFXNDIPO-QGZVFWFLSA-N
SMILES: O=C(C1=C2C=CC=C1)N(CCCCNC[C@H]3CCC4=CC=CC=C4O3)S2(=O)=O
Biological Activity: Repinotan (BAY x 3702 free base) is a potent, selective, brain-penetrant and orally active 5-HT1A receptor agonist, with Ki values of 0.19 nM (calf hippocampus), 0.25 nM (rat and human cortex), and 0.59 nM (rat hippocampus). Repinotan has a weak affinity for other related receptors. Repinotan has pronounced neuroprotective effects[1].
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Repinotan | Repinotan (BAY x 3702 free base) is a potent, selective, brain-penetrant and orally active 5-HT1A receptor agonist, with Ki values of 0.19 nM (calf hippocampus), 0.25 nM (rat and human cortex), and 0.59 nM (rat hippocampus). Repinotan has a weak affinity for other related receptors. Repinotan has pronounced neuroprotective effects. | |||||||||||||||||||||
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