145194-32-7
Chemical Structure
Y 25510
- CAS No.: 145194-32-7
- Formula:C19H22N4O3
- Molecular Weight:354.40
IUPAC Name: 2-(3-(4-((1-(dimethylamino)propan-2-yl)oxy)phenyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
InChIKey: DYLPVOLNSXUKPG-UHFFFAOYSA-N
SMILES: O=C(O)CN1N=C(C2=CC=C(OC(C)CN(C)C)C=C2)C3=CC=CN=C31
Biological Activity: Y 25510 is a 1H-pyrazolo[3,4-b]pyridine-1-acetic acid derivative. Y 25510 stimulates production of cytokines (IL-1α, IL-1β, IL-10 and IL-6)[1][2].
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Y 25510 | Y 25510 is a 1H-pyrazolo[3,4-b]pyridine-1-acetic acid derivative. Y 25510 stimulates production of cytokines (IL-1α, IL-1β, IL-10 and IL-6). | |||||||||||||||||||||
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- [1]. Kusuhara H, et al. (+/-)-3-[4-(2-dimethylamino-1-methylethoxy)-phenyl]-1H-pyrazolo[3,4- B]pyridine-1-acetic acid (Y-25510) stimulates production of IL-1 beta and IL-6 at the level of messenger RNA expression in cultured human monocytes. Int J Immunopharmacol. 1996 Dec;18(12):719-28. [Content Brief]
- [2]. Hisadome M, et al. Enhancement of in vivo production of IL-1α and IL-6 in mice by Y-25510, a 1H-pyrazolo [3, 4-b] pyridine-1-acetic acid derivative. International journal of immunopharmacology, 1996, 18(6-7): 379-384.
Keywords