1452460-79-5
1452460-79-5
Chemical Structure
WCK-5153
- CAS No.: 1452460-79-5
- Formula:C12H19N5O7S
- Molecular Weight:377.37
IUPAC Name: (2S,5R)-7-oxo-2-(2-((S)-pyrrolidine-3-carbonyl)hydrazine-1-carbonyl)-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate
InChIKey: NAURQUDBIPQVFZ-YIZRAAEISA-N
SMILES: O=C([C@H]1CCNC1)NNC([C@H]2N(C(N3OS(=O)(O)=O)=O)C[C@H]3CC2)=O
Biological Activity: WCK-5153 is a Penicillin-Binding Protein 2 (PBP2) inhibitor with an IC50 of 0.14 μg/ml (for P. aeruginosa PBP2) and acts as a β-lactam enhancer against Pseudomonas aeruginosa. WCK-5153 can be used in studies of multidrug-resistant (MDR) pathogens[1].
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WCK-5153 | WCK-5153 is a Penicillin-Binding Protein 2 (PBP2) inhibitor with an IC50 of 0.14 μg/ml (for P. aeruginosa PBP2) and acts as a β-lactam enhancer against Pseudomonas aeruginosa. WCK-5153 can be used in studies of multidrug-resistant (MDR) pathogens. | |||||||||||||||||||||
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References
Keywords
