1454658-89-9
1454658-89-9
Chemical Structure
MW108 hydrochloride
Synonym(s): MW01-11-108SRM hydrochloride
- CAS No.: 1454658-89-9
- Formula:C21H19ClN4
- Molecular Weight:362.86
IUPAC Name: N,N-dimethyl-6-(naphthalen-2-yl)-5-(pyridin-4-yl)pyridazin-3-amine hydrochloride
InChIKey: YCTPOOSUMJYWMU-UHFFFAOYSA-N
SMILES: CN(C)C1=NN=C(C2=CC=C3C=CC=CC3=C2)C(C4=CC=NC=C4)=C1.[H]Cl
Biological Activity: MW108 (MW01-11-108SRM) hydrochloride is a selective and CNS-penetrant p38αMAPK inhibitor with a Ki of 114 nM. MW108 hydrochloride ameliorates beta-amyloid induced synaptic and cognitive dysfunction[1].
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MW108 hydrochloride | MW108 (MW01-11-108SRM) hydrochloride is a selective and CNS-penetrant p38αMAPK inhibitor with a Ki of 114 nM. MW108 hydrochloride ameliorates beta-amyloid induced synaptic and cognitive dysfunction. | |||||||||||||||||||||
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