1454847-05-2
1454847-05-2
Chemical Structure
TAM-IN-1
- CAS No.: 1454847-05-2
- Formula:C21H22ClFN6O3
- Molecular Weight:460.89
IUPAC Name: (R)-25-amino-56-chloro-55-fluoro-11-(2-hydroxyethyl)-13,4,7-trimethyl-11H-3-oxa-7-aza-2(2,6)-pyrazina-1(4,5)-pyrazola-5(1,2)-benzenacyclooctaphan-6-one
InChIKey: VFRJEYJOQSRCNK-LLVKDONJSA-N
SMILES: OCCN1C2=C(C(C)=N1)C3=CN=C(N)C(O[C@@H](C4=C(Cl)C(F)=CC=C4C(N(C2)C)=O)C)=N3
Biological Activity: TAM-IN-1 (compound 1) is a potent macrocyclic inhibitor of Axl and Mer, with Kis of 130 pM and <50 pM, respectively[1].
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TAM-IN-1 | TAM-IN-1 (compound 1) is a potent macrocyclic inhibitor of Axl and Mer, with Kis of 130 pM and <50 pM, respectively. | |||||||||||||||||||||
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References
Keywords
