146764-58-1
Chemical Structure
2-Methylcitric acid-d3
Synonym(s): Methylcitric acid-d3
- CAS No.: 146764-58-1
- Formula:C7H7D3O7
- Molecular Weight:209.17
IUPAC Name: 2-hydroxybutane-1,2,3-tricarboxylic-4,4,4-d3 acid
InChIKey: YNOXCRMFGMSKIJ-FIBGUPNXSA-N
SMILES: [2H]C([2H])([2H])C(C(O)=O)C(C(O)=O)(O)CC(O)=O
Biological Activity: 2-Methylcitric acid-d3 is the deuterium labeled 2-Methylcitric acid. 2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate[1].
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2-Methylcitric acid-d3 | 98.90% | 2-Methylcitric acid-d3 is the deuterium labeled 2-Methylcitric acid. 2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate. | ||||||||||||||||||||
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2-Methylcitric acid (Standard) | ≥98% | Omeprazole (sodium) (Standard) is the analytical standard of Omeprazole (sodium). This product is intended for research and analytical applications. Omeprazole sodium (H 16868 sodium), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole sodium shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole sodium also inhibits growth of Gram-positive and Gram-negative bacteria. Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). | ||||||||||||||||||||
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2-Methylcitric acid | 99.72% | 2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate. | ||||||||||||||||||||
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