147865-49-4
147865-49-4
Chemical Structure
FK 633
Synonym(s): FR-144633
- CAS. Nr.: 147865-49-4
- Formula:C20H28N4O7
- Molecular Weight:436.46
IUPAC Name: (S)-3-(4-(4-carbamimidoylphenoxy)butanamido)-4-(((S)-1-carboxy-2-methylpropyl)amino)-4-oxobutanoic acid
InChIKey: JFCXCBBSUORTNS-YOEHRIQHSA-N
SMILES: CC(C)[C@@H](C(O)=O)NC([C@H](CC(O)=O)NC(CCCOC1=CC=C(C(N)=N)C=C1)=O)=O
Biological Activity: FK 633 (FR-144633) is a fibrinogen inhibitor and peptide mimetic GPⅡbⅡa receptor antagonist. FK 633 has anti-platelet and anti-thrombotic effects. FK 633 inhibits ADP-, collagen-, thrombin-, and PAF-induced platelet aggregation with IC50 values of 103, 87, 98, and 239 nM, respectively[1][2].
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FK 633 | FK 633 (FR-144633) is a fibrinogen inhibitor and peptide mimetic GPⅡbⅡa receptor antagonist. FK 633 has anti-platelet and anti-thrombotic effects. FK 633 inhibits ADP-, collagen-, thrombin-, and PAF-induced platelet aggregation with IC50 values of 103, 87, 98, and 239 nM, respectively. | |||||||||||||||||||||
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