149092-45-5
Chemical Structure
Mycosporine 2 glycine
- CAS No.: 149092-45-5
- Formula:C12H18N2O7
- Molecular Weight:302.28
InChIKey: NCZZDMCBYGVEGP-ACLQVGRQSA-N
SMILES: COC1=C(NCC(O)=O)C[C@@](O)(CO)C/C1=N\CC(O)=O
Biological Activity: Mycosporine 2 glycine is an anti-inflammatory agent and TYRP1 inhibitor. Mycosporine 2 glycine inhibits the expression of inflammatory genes and reduces nitric oxide production. Mycosporine 2 glycine binds tightly to the active pocket of TYRP1 and inhibits the activity of melanogenesis-related enzymes. Mycosporine 2 glycine can be used in the research of hyperpigmentation and inflammation-related diseases[1][2].
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Mycosporine 2 glycine | Mycosporine 2 glycine is an anti-inflammatory agent and TYRP1 inhibitor. Mycosporine 2 glycine inhibits the expression of inflammatory genes and reduces nitric oxide production. Mycosporine 2 glycine binds tightly to the active pocket of TYRP1 and inhibits the activity of melanogenesis-related enzymes. Mycosporine 2 glycine can be used in the research of hyperpigmentation and inflammation-related diseases. | |||||||||||||||||||||
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- [1]. Tarasuntisuk S, et al. Mycosporine-2-glycine exerts anti-inflammatory and antioxidant effects in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. Arch Biochem Biophys. 2019;662:33-39. [Content Brief]
- [2]. Amin N, et al. Mycosporine-Like Amino Acids as a Potential Inhibitor of Tyrosinase-Related Protein 1: Computational Screening, Pharmacokinetics, and Molecular Dynamics Simulation. Mol Biotechnol. 2025;67(4):1674-1694. [Content Brief]
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