150399-22-7
Chemical Structure
SB-201993
- CAS No.: 150399-22-7
- Formula:C32H37NO6S
- Molecular Weight:563.70
IUPAC Name: (E)-3-((((6-(2-carboxyvinyl)-5-((8-(4-methoxyphenyl)octyl)oxy)pyridin-2-yl)methyl)thio)methyl)benzoic acid
InChIKey: QQUXZUFSDIOIFJ-HTXNQAPBSA-N
SMILES: O=C(O)C1=CC=CC(CSCC2=NC(/C=C/C(O)=O)=C(OCCCCCCCCC3=CC=C(OC)C=C3)C=C2)=C1
Biological Activity: SB-201993 is a selective leukotriene B₄ (LTB4) receptor antagonist with a Ki=7.6 nM for LTB4 receptors on human inflammatory cells. SB-201993 inhibits calcium mobilization in inflammatory cells and 5-lipoxygenase activity, exerting anti-inflammatory effects. SB-201993 is promising for research of inflammatory diseases (e.g., dermatitis, arthritis)[1].
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SB-201993 | SB-201993 is a selective leukotriene B₄ (LTB4) receptor antagonist with a Ki=7.6 nM for LTB4 receptors on human inflammatory cells. SB-201993 inhibits calcium mobilization in inflammatory cells and 5-lipoxygenase activity, exerting anti-inflammatory effects. SB-201993 is promising for research of inflammatory diseases (e.g., dermatitis, arthritis). | |||||||||||||||||||||
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Keywords
