1522418-41-2
Chemical Structure
Lanabecestat camsylate
Synonym(s): LY3314814 camsylate; AZD3293 camsylate
- CAS No.: 1522418-41-2
- Formula:C36H44N4O5S
- Molecular Weight:644.82
IUPAC Name: (1r,1'R,4R)-4-methoxy-5''-methyl-6'-(5-(prop-1-yn-1-yl)pyridin-3-yl)-3'H-dispiro[cyclohexane-1,2'-indene-1',2''-imidazol]-4''-amine ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate
InChIKey: PEOILZBROWEGCC-FUGZSDNTSA-N
SMILES: CC#CC1=CC(C2=CC([C@@]34N=C(C)C(N)=N4)=C(C[C@@]53CC[C@@H](OC)CC5)C=C2)=CN=C1.O=S(C[C@@]6(C7(C)C)C(C[C@H]7CC6)=O)(O)=O
Biological Activity: Lanabecestat (AZD3293; LY3314814) camsylate is a potent, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM. Lanabecestat camsylate is used for the research of Alzheimer's disease[1].
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Lanabecestat camsylate | Lanabecestat (AZD3293; LY3314814) camsylate is a potent, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM. Lanabecestat camsylate is used for the research of Alzheimer's disease. | |||||||||||||||||||||
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Keywords
