1527523-39-2
Chemical Structure
GNE-955
- CAS No.: 1527523-39-2
- Formula:C22H24N8O
- Molecular Weight:416.48
IUPAC Name: (S)-1-(3-methoxy-6-(6-(6-methylpyrazin-2-yl)-1H-pyrazolo[4,3-c]pyridin-1-yl)pyridin-2-yl)piperidin-3-amine
InChIKey: FPBWUTAWSOLPQI-INIZCTEOSA-N
SMILES: CC1=CN=CC(C2=CC3=C(C=NN3C4=CC=C(OC)C(N5CCC[C@H](N)C5)=N4)C=N2)=N1
Biological Activity: GNE-955 is a potent and orally active pan Pim kinase inhibitor with Kis of 0.018, 0.11, 0.08 nM for Pim1, Pim2, Pim3, respectively.
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GNE-955 | GNE-955 is a potent and orally active pan Pim kinase inhibitor with Kis of 0.018, 0.11, 0.08 nM for Pim1, Pim2, Pim3, respectively. | |||||||||||||||||||||
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Keywords