154612-31-4
Chemical Structure
BILA 1906 BS
- CAS No.: 154612-31-4
- Formula:C41H52N6O4S
- Molecular Weight:724.95
IUPAC Name: N-((S)-1-(((2S,3R)-4-((2S,4R)-2-(tert-butylcarbamoyl)-4-((pyridin-3-ylmethyl)thio)piperidin-1-yl)-3-hydroxy-1-phenylbutan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)quinoline-2-carboxamide
InChIKey: IMPWGYVYFQPDFN-SZNOJMITSA-N
SMILES: O=C(N[C@@H](C(C)C)C(N[C@H]([C@@H](CN1[C@@H](C[C@@H](CC1)SCC2=CC=CN=C2)C(NC(C)(C)C)=O)O)CC3=CC=CC=C3)=O)C4=NC5=CC=CC=C5C=C4
Biological Activity: BILA 1906 BS is a HIV protease inhibitor. BILA 1906 BS prevents HIV-1 replication via inhibition of viral protease-mediated cleavage of Gag and Gag-Pol polyprotein precursors during virion maturation. BILA 1906 BS blocks maturation of p24 proteins in wild-type HIV-1, impairing polyprotein processing and viral maturation. BILA 1906 BS can be used for the research of human immunodeficiency virus type 1 (HIV-1) infection[1].
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BILA 1906 BS | BILA 1906 BS is a HIV protease inhibitor. BILA 1906 BS prevents HIV-1 replication via inhibition of viral protease-mediated cleavage of Gag and Gag-Pol polyprotein precursors during virion maturation. BILA 1906 BS blocks maturation of p24 proteins in wild-type HIV-1, impairing polyprotein processing and viral maturation. BILA 1906 BS can be used for the research of human immunodeficiency virus type 1 (HIV-1) infection. | |||||||||||||||||||||
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