154934-68-6

SP100030 analogue 1 Chemical Structure
154934-68-6

Chemical Structure

SP100030 analogue 1

  • CAS No.: 154934-68-6
  • Formula:C13H5ClF7N3O
  • Molecular Weight:387.64

InChIKey: UAESMOLVKWXOPC-UHFFFAOYSA-N

SMILES: O=C(C1=CN=C(N=C1C(F)(F)F)Cl)NC2=CC(F)=CC(C(F)(F)F)=C2

Biological Activity: SP100030 analogue 1 (compound 11), a SP100030 (HY-110177) analogue, is a selective inhibitor of transcriptional activation (SITA) with an EC50 of 137 nM for suppressing the XPO1-dependent upregulation of IL2 by Jurkat-based IL2-Luc reporter assay[1].

Cat. No. Product Name Purity Description Pricing
HY-163902
SP100030 analogue 1 SP100030 analogue 1 (compound 11), a SP100030 (HY-110177) analogue, is a selective inhibitor of transcriptional activation (SITA) with an EC50 of 137 nM for suppressing the XPO1-dependent upregulation of IL2 by Jurkat-based IL2-Luc reporter assay.
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