154934-68-6
154934-68-6
Chemical Structure
SP100030 analogue 1
- CAS No.: 154934-68-6
- Formula:C13H5ClF7N3O
- Molecular Weight:387.64
InChIKey: UAESMOLVKWXOPC-UHFFFAOYSA-N
SMILES: O=C(C1=CN=C(N=C1C(F)(F)F)Cl)NC2=CC(F)=CC(C(F)(F)F)=C2
Biological Activity: SP100030 analogue 1 (compound 11), a SP100030 (HY-110177) analogue, is a selective inhibitor of transcriptional activation (SITA) with an EC50 of 137 nM for suppressing the XPO1-dependent upregulation of IL2 by Jurkat-based IL2-Luc reporter assay[1].
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SP100030 analogue 1 | SP100030 analogue 1 (compound 11), a SP100030 (HY-110177) analogue, is a selective inhibitor of transcriptional activation (SITA) with an EC50 of 137 nM for suppressing the XPO1-dependent upregulation of IL2 by Jurkat-based IL2-Luc reporter assay. | |||||||||||||||||||||
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