155048-06-9
Chemical Structure
Butein tetramethyl ether
- CAS No.: 155048-06-9
- Formula:C19H20O5
- Molecular Weight:328.36
InChIKey: XKVLLUWABVOODQ-WEVVVXLNSA-N
SMILES: COC(C=C1/C=C/C(C2=C(C=C(C=C2)OC)OC)=O)=C(C=C1)OC
Biological Activity: Butein tetramethyl ether (Compound 20) is a potent and selective breast cancer resistance protein/ATP-binding cassette subfamily G member 2 (BCRP/ABCG2) inhibitor. Butein tetramethyl ether has inhibitory potencies against MCF-7 MX and MDCK BCRP cells with IC50 values of 2.2 and 1.03 μM, respectively. Butein tetramethyl ether is promising for research of cancers[1].
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Butein tetramethyl ether | Butein tetramethyl ether (Compound 20) is a potent and selective breast cancer resistance protein/ATP-binding cassette subfamily G member 2 (BCRP/ABCG2) inhibitor. Butein tetramethyl ether has inhibitory potencies against MCF-7 MX and MDCK BCRP cells with IC50 values of 2.2 and 1.03 μM, respectively. Butein tetramethyl ether is promising for research of cancers. | |||||||||||||||||||||
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Keywords