15622-65-8
Chemical Structure
Molindone (hydrochloride)
Synonym(s): EN-1733A
- No. CAS: 15622-65-8
- Formula:C16H25ClN2O2
- Molecular Weight:312.83
IUPAC Name: 3-ethyl-2-methyl-5-(morpholinomethyl)-1,5,6,7-tetrahydro-4H-indol-4-one hydrochloride
InChIKey: GQWNECFJGBQMBO-UHFFFAOYSA-N
SMILES: O=C1C2=C(NC(C)=C2CC)CCC1CN3CCOCC3.[H]Cl
Biological Activity: Molindone hydrochloride (EN-1733A) is an orally active and brain-penetrant dopamine D2/D5 receptor antagonist. Molindone hydrochloride shows antipsychotic and antidepressant-like activities. Molindone hydrochloride suppresses spontaneous locomotion, and antagonizes apomorphine-induced emesis. Molindone hydrochloride can be used for the research of neurological disease[1][2].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Molindone (hydrochloride) | 99.81% | Molindone hydrochloride (EN-1733A) is an orally active and brain-penetrant dopamine D2/D5 receptor antagonist. Molindone hydrochloride shows antipsychotic and antidepressant-like activities. Molindone hydrochloride suppresses spontaneous locomotion, and antagonizes apomorphine-induced emesis. Molindone hydrochloride can be used for the research of neurological disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Molindone hydrochloride (Standard) | ≥98% | Molindone hydrochloride (Standard) is the analytical standard of Molindone hydrochloride (HY-B1017). This product is intended for research and analytical applications. Molindone hydrochloride (EN-1733A) is an orally active and brain-penetrant dopamine D2/D5 receptor antagonist. Molindone hydrochloride shows antipsychotic and antidepressant-like activities. Molindone hydrochloride suppresses spontaneous locomotion, and antagonizes apomorphine-induced emesis. Molindone hydrochloride can be used for the research of neurological disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Krishna G, et al. Toxicity assessment of molindone hydrochloride, a dopamine D2/D5 receptor antagonist in juvenile and adult rats. Toxicol Mech Methods. 2017;27(5):352-362. [Content Brief]
- [2]. Rubin A A, et al. Psychopharmacological profile of molindone[J]. Nature, 1967, 216(5115): 578-579. [Content Brief]
