158994-32-2
158994-32-2
Chemical Structure
Salviandulin E
- CAS No.: 158994-32-2
- Formula:C20H16O6
- Molecular Weight:352.34
InChIKey: OHRYPZSDRFBQMN-ZINOCKGTSA-N
SMILES: CC1=C2[C@@]3(C=CC4=C1[C@H](C5=COC=C5)OC4=O)C(C(OC3)=O)=C[C@@H](C2)O
Biological Activity: Salviandulin E is a diterpenoid compound that can be isolated from Salvia leucantha CAV.. Salviandulin E shows antitrypanosomal activity against T. b. brucei GUTat 3.1 parasites with an IC50 value of 0.72 µg/mL[1][2].
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Salviandulin E | Salviandulin E is a diterpenoid compound that can be isolated from Salvia leucantha CAV.. Salviandulin E shows antitrypanosomal activity against T. b. brucei GUTat 3.1 parasites with an IC50 value of 0.72 µg/mL. | |||||||||||||||||||||
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References
- [1]. Narukawa Y, et al. A novel diterpenoid with a rearranged neoclerodane skeleton from Salvia leucantha CAV. J Nat Med. 2006 Jul;60(3):206-209. [Content Brief]
- [2]. Aoyagi Y, et al. Semisynthesis of salviandulin E analogues and their antitrypanosomal activity. Bioorg Med Chem Lett. 2014 Jan 15;24(2):442-6. [Content Brief]
