A novel diterpenoid with a rearranged neoclerodane skeleton from Salvia leucantha CAV

  • J Nat Med. 2006 Jul;60(3):206-209. doi: 10.1007/s11418-006-0037-3.
Yuji Narukawa  1 ,  Keiichiro Hatano  2 ,  Tadahiro Takeda  3
Affiliations
  • 1. Kyoritsu University of Pharmacy, Shibakoen 1-5-30, Minato-ku, Tokyo 105-8512, Japan.
  • 2. Graduate School of Pharmaceutical Science, Nagoya City University, Tanabe-dori, Mizuho-ku, Nagoya 467-8603, Japan.
  • 3. Kyoritsu University of Pharmacy, Shibakoen 1-5-30, Minato-ku, Tokyo 105-8512, Japan. [email protected].
PMID: 29435878 DOI: 10.1007/s11418-006-0037-3
Abstract

A new diterpenoid with a rearranged neoclerodane skeleton, spiroleucantholide (compound "S1"), along with four known diterpenoids-salvifaricin (compound "S2"), isosalvipuberulin (compound "S3"), salvileucantholide (compound "S4"), and salviandulin E (compound "S5")-was isolated from the aerial parts of Salvia leucantha CAV.. The structures were established by spectroscopic methods, including the X-ray analysis of spiroleucantholide (S1).

Keywords
Labiatae; Neoclerodane-related compounds; Salvia leucantha CAV.; Spiroleucantholide.
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