160341-09-3
Chemical Structure
S-3483
- CAS. Nr.: 160341-09-3
- Formula:C26H27ClO8
- Molecular Weight:502.94
IUPAC Name: (1S,3R,4R,5R)-1-(((1R,2S)-2-(4-chlorophenyl)cyclopropyl)methoxy)-3,4-dihydroxy-5-(((E)-3-(4-hydroxyphenyl)acryloyl)oxy)cyclohexane-1-carboxylic acid
InChIKey: GXYXOQNLWDVZCK-UCIPEFGISA-N
SMILES: O=C([C@]1(OC[C@H]2[C@@H](C3=CC=C(Cl)C=C3)C2)C[C@@H](O)[C@@H](O)[C@H](OC(/C=C/C4=CC=C(O)C=C4)=O)C1)O
Biological Activity: S-3483, a Chlorogenic acid (HY-N0055) derivative, is a reversible, linear competitive glucose-6-phosphatase (Glc-6-Pase) system inhibitor. S-3483 inhibits Glc-6-Pase with a Ki 129 nM in rat liver microsomes. S-3483 specifically inhibits Glc-6-P transporter of renal and liver microsomes[1].
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S-3483 | S-3483, a Chlorogenic acid (HY-N0055) derivative, is a reversible, linear competitive glucose-6-phosphatase (Glc-6-Pase) system inhibitor. S-3483 inhibits Glc-6-Pase with a Ki 129 nM in rat liver microsomes. S-3483 specifically inhibits Glc-6-P transporter of renal and liver microsomes. | |||||||||||||||||||||
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Keywords
