1609980-80-4
Chemical Structure
N-Acetylhexosamine kinase (NahK)
- CAS No.: 1609980-80-4
- Formula:N/A
- Molecular Weight:N/A
IUPAC Name: 2-hydroxy-4-((2-hydroxy-4-methoxy-3,6-dimethylbenzoyl)oxy)-3,6-dimethylbenzoic acid
SMILES: [N-Acetylhexosamine kinase (NahK)]
Biological Activity: N-Acetylhexosamine kinase (NahK) is an anomeric kinase acting on a glucose-type substrate. N-Acetylhexosamine kinase catalyzes the phosphorylation of GlcNAc or GalNAc at the anomeric C1 position with ATP to form N-acetylhexosamine 1-phosphate (GlcNAc-1P/GalNAc-1P)[1][2].
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N-Acetylhexosamine kinase (NahK) | N-Acetylhexosamine kinase (NahK) is an anomeric kinase acting on a glucose-type substrate. N-Acetylhexosamine kinase catalyzes the phosphorylation of GlcNAc or GalNAc at the anomeric C1 position with ATP to form N-acetylhexosamine 1-phosphate (GlcNAc-1P/GalNAc-1P). | |||||||||||||||||||||
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- [1]. Sato M, et al. Open-close structural change upon ligand binding and two magnesium ions required for the catalysis of N-acetylhexosamine 1-kinase. Biochim Biophys Acta. 2015 May;1854(5):333-40. [Content Brief]
- [2]. Wang KC, et al. Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes. Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1401-10. [Content Brief]
Keywords