1612191-95-3
![9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-154733.gif "9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine Chemical Structure")
Chemical Structure
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine
- CAS No.: 1612191-95-3
- Formula:C18H16FN5O3
- Molecular Weight:369.35
IUPAC Name: (2R,3S,4S,5R)-4-fluoro-5-(hydroxymethyl)-2-(6-(5-(prop-1-yn-1-yl)pyridin-3-yl)-9H-purin-9-yl)tetrahydrofuran-3-ol
InChIKey: CGCIVQJBWZRBCA-ZHCAMHROSA-N
SMILES: O[C@@H]1[C@H](F)[C@@H](CO)O[C@H]1N2C(N=CN=C3C4=CN=CC(C#CC)=C4)=C3N=C2
Biological Activity: 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine | 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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