1616752-12-5
1616752-12-5
Chemical Structure
PDK4-IN-2
- CAS No.: 1616752-12-5
- Formula:C13H10O5
- Molecular Weight:246.22
InChIKey: LYFCHMYCNHQFNJ-UHFFFAOYSA-N
SMILES: COC(C1=CC2=C(C(O)=C1)C(C=C(C2=O)C)=O)=O
Biological Activity: PDK4-IN-2 (compound 8) is a pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 of 46 µM. PDK4-IN-2 improves ejection fraction of failing hearts by regulating bioenergetics via activation of the tricarboxylic acid cycle[1].
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PDK4-IN-2 | PDK4-IN-2 (compound 8) is a pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 of 46 µM. PDK4-IN-2 improves ejection fraction of failing hearts by regulating bioenergetics via activation of the tricarboxylic acid cycle. | |||||||||||||||||||||
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