1620634-65-2
1620634-65-2
Chemical Structure
SIRT-IN-7
- CAS No.: 1620634-65-2
- Formula:C24H16BrClN2OS
- Molecular Weight:495.82
InChIKey: QJIYVRGTJZFUDL-UHFFFAOYSA-N
SMILES: ClC1=CC2=C(N=C(NC(C3=C(C=CC4=C3C=CC=C4)O)C5=CC=C(C=C5)Br)S2)C=C1
Biological Activity: SIRT-IN-7 (Compound 7ba) is a SIRT inhibitor. SIRT-IN-7 can inhibit the expression of SIRT1, SIRT2, and SIRT3, and increase the acetylation and activation of p53. SIRT-IN-7 can inhibit the proliferation, and induce apoptosis and autophagy of breast cancer cells. SIRT-IN-7 has anti-tumor activity[1].
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SIRT-IN-7 | SIRT-IN-7 (Compound 7ba) is a SIRT inhibitor. SIRT-IN-7 can inhibit the expression of SIRT1, SIRT2, and SIRT3, and increase the acetylation and activation of p53. SIRT-IN-7 can inhibit the proliferation, and induce apoptosis and autophagy of breast cancer cells. SIRT-IN-7 has anti-tumor activity. | |||||||||||||||||||||
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References
Keywords
