1622452-45-2
1622452-45-2
Chemical Structure
COX-2/Aromatase-IN-2
- CAS No.: 1622452-45-2
- Formula:C16H13N3O3
- Molecular Weight:295.29
InChIKey: VLGBPOVWRFASTA-VQHVLOKHSA-N
SMILES: O=C(N1N=NC2=CC=CC=C21)/C=C/C3=CC=C(O)C(OC)=C3
Biological Activity: COX-2/Aromatase-IN-2 is a potent dual inhibitor of COX-2 and aromatase. COX-2/Aromatase-IN-2 can simultaneously inhibit COX-2 and aromatase, suppress inflammation and induce proliferation inhibition of breast cancer cells. COX-2/Aromatase-IN-2 exerts anti-breast cancer and anti-inflammatory effects in the MCF-7 breast cancer cell and carrageenan-induced rat paw edema model. COX-2/Aromatase-IN-2 can be used for the study of inflammation and breast cancer[1].
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COX-2/Aromatase-IN-2 | COX-2/Aromatase-IN-2 is a potent dual inhibitor of COX-2 and aromatase. COX-2/Aromatase-IN-2 can simultaneously inhibit COX-2 and aromatase, suppress inflammation and induce proliferation inhibition of breast cancer cells. COX-2/Aromatase-IN-2 exerts anti-breast cancer and anti-inflammatory effects in the MCF-7 breast cancer cell and carrageenan-induced rat paw edema model. COX-2/Aromatase-IN-2 can be used for the study of inflammation and breast cancer. | |||||||||||||||||||||
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