162401-62-9
Chemical Structure
DGM
- CAS No.: 162401-62-9
- Formula:C12H12F2O4
- Molecular Weight:258.22
IUPAC Name: 3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzoic acid
InChIKey: IGFDIFLMMLWKKY-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(OC(F)F)C(OCC2CC2)=C1
Biological Activity: DGM is an inhibitor of the TGF-β1/Smad signaling pathway with significant antifibrotic effects. DGM inhibits the epithelial-mesenchymal transition (EMT) process in alveolar epithelial cells and slows the progression of pulmonary fibrosis in vivo by reducing lung inflammation, improving lung function, and decreasing extracellular matrix (ECM) remodeling. DGM can be used in research on idiopathic pulmonary fibrosis (IPF) and EMT-related diseases[1].
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DGM | 99.99% | DGM is an inhibitor of the TGF-β1/Smad signaling pathway with significant antifibrotic effects. DGM inhibits the epithelial-mesenchymal transition (EMT) process in alveolar epithelial cells and slows the progression of pulmonary fibrosis in vivo by reducing lung inflammation, improving lung function, and decreasing extracellular matrix (ECM) remodeling. DGM can be used in research on idiopathic pulmonary fibrosis (IPF) and EMT-related diseases. | ||||||||||||||||||||
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Keywords
