1627696-53-0
1627696-53-0
Chemical Structure
LY3177833 monhydrate
- CAS No.: 1627696-53-0
- Formula:C16H14FN5O2
- Molecular Weight:327.31
IUPAC Name: (R)-3-(5-fluoropyrimidin-4-yl)-3-methyl-6-(1H-pyrazol-4-yl)isoindolin-1-one hydrate
InChIKey: WSICFXBHDWUFRU-PKLMIRHRSA-N
SMILES: O=C1N[C@@](C)(C2=NC=NC=C2F)C3=C1C=C(C4=CNN=C4)C=C3.[H]O[H]
Biological Activity: LY3177833 (Example 4) monhydrate is an orally active CDC7 and pMCM2 inhibitor with IC50 values of 3.3 nM and 290 nM, respectively. LY3177833 monhydrate is a senescence inducer[1][2].
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LY3177833 monhydrate | LY3177833 (Example 4) monhydrate is an orally active CDC7 and pMCM2 inhibitor with IC50 values of 3.3 nM and 290 nM, respectively. LY3177833 monhydrate is a senescence inducer. | |||||||||||||||||||||
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