1628343-77-0
1628343-77-0
Chemical Structure
ARN726
- CAS. Nr.: 1628343-77-0
- Formula:C14H24N2O3
- Molecular Weight:268.35
IUPAC Name: 4-cyclohexylbutyl (S)-(2-oxoazetidin-3-yl)carbamate
InChIKey: FNLUJRBWJBUJTC-LBPRGKRZSA-N
SMILES: O=C(OCCCCC1CCCCC1)N[C@@H]2C(NC2)=O
Biological Activity: ARN726 is a potent NAAA (N-acylethanolamine acid amidase) inhibitor with an IC50 of 0.073 µM. ARN726 decreases alcohol self-administration in a dose-dependent manner[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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ARN726 | 98.10% | ARN726 is a potent NAAA (N-acylethanolamine acid amidase) inhibitor with an IC50 of 0.073 µM. ARN726 decreases alcohol self-administration in a dose-dependent manner. | ||||||||||||||||||||
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References
- [1]. Fotio Y, et al. N-acylethanolamine acid amidase (NAAA) inhibition decreases the motivation for alcohol in Marchigian Sardinian alcohol-preferring rats. Psychopharmacology (Berl). 2021 Jan;238(1):249-258. [Content Brief]
- [2]. Petracca R, et al. Novel activity-based probes for N-acylethanolamine acid amidase. Chem Commun (Camb). 2017 Aug 22;53(86):11810-11813. [Content Brief]
