163000-63-3
Chemical Structure
Neboglamine
Synonym(s): CR-2249; XY-2401
- CAS No.: 163000-63-3
- Formula:C13H24N2O3
- Molecular Weight:256.34
IUPAC Name: (S)-4-amino-5-((4,4-dimethylcyclohexyl)amino)-5-oxopentanoic acid
InChIKey: VCRGLZYPNNAVRP-JTQLQIEISA-N
SMILES: OC(CC[C@H](N)C(NC1CCC(C)(CC1)C)=O)=O
Biological Activity: Neboglamine (CR-2249; XY-2401) is a modulator for N-methyl-D-aspartate (NMDA) receptor. Neboglamine increases the levels of fos-like immunoreactivity (FLI)-positive cells in the prefrontal cortex, nucleus accumbens, and lateral septal nucleus in rat models, .restores NMDA (HY-17551) -mediated neurotransmitter release, and inhibits phencyclidine-induced hyperlocomotion[1].
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Neboglamine | Neboglamine (CR-2249; XY-2401) is a modulator for N-methyl-D-aspartate (NMDA) receptor. Neboglamine increases the levels of fos-like immunoreactivity (FLI)-positive cells in the prefrontal cortex, nucleus accumbens, and lateral septal nucleus in rat models, .restores NMDA (HY-17551) -mediated neurotransmitter release, and inhibits phencyclidine-induced hyperlocomotion. | |||||||||||||||||||||
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